Saturday, June 1, 2013
Black Cumin seed (Nigella sativa, Kalonji) protects against Paracetamol induced hepatotoxicity
Protective Effects of Ethanolic Extract of Nigella sativa Seed in Paracetamol Induced Acute Hepatotoxicity In vivo
D.S. Kushwah, M.T. Salman, P. Singh, V.K. Verma and A. Ahmad
Paracetamol overdose causes serious liver necrosis. Hepatoprotective activity of ethanolic extract of Nigella sativa in Paracetamol induced acute hepatotoxicity was investigated in rats. Fasted male Wistar rats were orally treated with Nigella sativa extract in graded doses for 5 days followed by Nigella sativa extract and paracetamol 3 g kg-1 on 6 and 7th day. Circulatory liver markers and reduced glutathione (GSH) levels were estimated and histopathological study of liver performed. Paracetamol caused a significant increase in serum alkaline phosphatase, glutamic oxaloacetic transaminase, glutamic pyruvic transaminase and total Bilirubin and a significant decrease in GSH compared to control. Nigella sativa pretreatment significantly prevented the increase in liver enzymes and total bilirubin and decrease in GSH level as compared to paracetamol group. Liver histopathology showed marked reduction in sinusoidal dilatation, midzonal necrosis, portal triaditis and occasional apoptosis in Nigella sativa extract treated groups as compared to group receiving only paracetamol. Nigella sativa extract possesses hepatoprotective action against paracetamol induced acute hepatoxicity. Further research is needed to advocate its prophylactic use for drug induced hepatotoxicity
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Thursday, March 21, 2013
Inhibition of Key Digestive Enzymes Related to Diabetes and Hyperlipidemia and Protection of Liver-Kidney Functions by Trigonelline in Diabetic Rats
Research on beneficial effects of active component of Trignella, commonly called as Methi Scientia Pharmaceutica
Saturday, March 9, 2013
Tuesday, March 5, 2013
Tuesday, January 15, 2013
Saturday, December 29, 2012
Fwd: Top 10 ProductiveMuslim.com Posts of 2012
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From: ProductiveMuslim <news@productivemuslim.com>
Date: 29 December 2012 00:41
Subject: Top 10 ProductiveMuslim.com Posts of 2012
To: Mohd Tariq Salman <mtariqsalman@gmail.com>
From: ProductiveMuslim <news@productivemuslim.com>
Date: 29 December 2012 00:41
Subject: Top 10 ProductiveMuslim.com Posts of 2012
To: Mohd Tariq Salman <mtariqsalman@gmail.com>
ProductiveMuslim Ltd, Suite B, 29 Harley Street, W1G 9QR, London, United Kingdom.
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http://medicalresearch.blogspot.com
http://sites.google.com/site/homepagepharmacology/
Saturday, October 1, 2011
Fwd: Significance of Morning Prayer
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From: ALQURANIC <alquranic@yahoo.com>
Date: 30 September 2011 18:33
Subject: Significance of Morning Prayer
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[Sahih Bukhari : Volume 2, Book 21 Prayer at Night (Tahajjud), Number 245]
Narrated 'Abdullah (Radi Allah Anhu) : A person was mentioned before the Allah's Apostle (sal-allahu-alleihi-wasallam) and he was told that he had kept on sleeping till morning and had not got up for the prayer. The Prophet said, "Satan urinated in his ears."
[Sahih Bukhari : Volume 2, Book 21 Prayer at Night (Tahajjud), Number 246]
Narrated Abu Huraira (Radi Allah Anhu): Allah's Apostle (sal-allahu-alleihi-wasallam) said, "Our Lord, the Blessed, the Superior, comes every night down on the nearest Heaven to us when the last third of the night remains, saying: "Is there anyone to invoke Me, so that I may respond to invocation? Is there anyone to ask Me, so that I may grant him his request? Is there anyone seeking My forgiveness, so that I may forgive him?"
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From: ALQURANIC <alquranic@yahoo.com>
Date: 30 September 2011 18:33
Subject: Significance of Morning Prayer
To: "alquranic@yahoogroups.com" <alquranic@yahoogroups.com>
ALQURANIC Mail [The Best Guide ALQURAN] |
Assalam-u-Alaikum Wa Rahmatullahi Wa Barakatuhu,
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[65. Surah At-Talaq : Ayah 2-3] |
And whosoever keepeth his duty to Allah, Allah will appoint a way out for him. And He provides for him from (sources) he never could imagine. And if any one puts his trust in Allah, Allah will be sufficient for him. |
Significance of Morning Prayer |
[Sahih Bukhari : Volume 2, Book 21 Prayer at Night (Tahajjud), Number 243]
Narrated Abu Huraira (Radi Allah Anhu) Allah's Apostle (sal-allahu-alleihi-wasallam) said, "Satan puts three knots at the back of the head of any of you if he is asleep. On every knot he reads and exhales the following words, 'The night is long, so stay asleep.' When one wakes up and remembers Allah, one knot is undone; and when one performs ablution, the second knot is undone, and when one prays the third knot is undone and one gets up energetic with a good heart in the morning; otherwise one gets up lazy and with a mischievous heart."
Narrated Abu Huraira (Radi Allah Anhu) Allah's Apostle (sal-allahu-alleihi-wasallam) said, "Satan puts three knots at the back of the head of any of you if he is asleep. On every knot he reads and exhales the following words, 'The night is long, so stay asleep.' When one wakes up and remembers Allah, one knot is undone; and when one performs ablution, the second knot is undone, and when one prays the third knot is undone and one gets up energetic with a good heart in the morning; otherwise one gets up lazy and with a mischievous heart."
[Sahih Bukhari : Volume 2, Book 21 Prayer at Night (Tahajjud), Number 245]
Narrated 'Abdullah (Radi Allah Anhu) : A person was mentioned before the Allah's Apostle (sal-allahu-alleihi-wasallam) and he was told that he had kept on sleeping till morning and had not got up for the prayer. The Prophet said, "Satan urinated in his ears."
[Sahih Bukhari : Volume 2, Book 21 Prayer at Night (Tahajjud), Number 246]
Narrated Abu Huraira (Radi Allah Anhu): Allah's Apostle (sal-allahu-alleihi-wasallam) said, "Our Lord, the Blessed, the Superior, comes every night down on the nearest Heaven to us when the last third of the night remains, saying: "Is there anyone to invoke Me, so that I may respond to invocation? Is there anyone to ask Me, so that I may grant him his request? Is there anyone seeking My forgiveness, so that I may forgive him?"
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Dr. Mohd. Tariq Salman, MD
Assistant Professor,
Department of Pharmacology,
Era's Lucknow Medical College,
Sarfarazganj, Hardoi Road,
Lucknow.
http://medicalresearch.blogspot.com
http://sites.google.com/site/homepagepharmacology/
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